This study contributes valuable evidence towards improving bone tissue processing and histopathological diagnosis in Tanzania. The study compared three concentrations of formic acid-formalin (10%, 15%, and 20%) to assess their effects on decalcification time, ease of tissue sectioning, and the microscopic quality of bone tissue. Key findings: - Faster decalcification: 20% formic acid-formalin achieved decalcification in an average of 42 days, compared with 51.2 days for 15% and 56.3 days for 10%. - Easier tissue sectioning: 82.5% of bone tissue pieces treated with 20% concentration were classified as easy to section. - Better histological quality: 61.3% of samples treated with 20% concentration demonstrated good microscopic quality.

Summary as published by the college when announcing this work. See the journal article for the full abstract.