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St. Francis University College of Health and Allied Sciences (SFUCHAS)

Discipline • Diligence • Excellence

Journal article Directorate of Research, Partnerships and Community Services

Epidemiological Profile of Leprosy Cases at Nazareti Leprosy Center, Tanzania: A Retrospective Analysis (2000-2024)

PLOS Neglected Tropical Diseases

Authors

  • Prof. Robert Machangu

  • Jacob Noah

  • Dr. Gabriel Upunda

  • Dr. Jovin Tibenderana

Abstract

, published in PLOS Neglected Tropical Diseases.

The study examined 801 leprosy (Hansen's disease) cases diagnosed at Nazareti Leprosy Center, Ifakara, over a 25-year period and identified important changes in the epidemiological profile of the disease.

Key findings include: - Leprosy case notifications increased by an average of 4.0% annually over the study period. - Multibacillary (MB) leprosy accounted for 62.7% of cases and increased significantly over time. - Grade 1 disability at diagnosis was the most common disability grade, affecting 52.7% of cases. - Cases among males and adults aged 50 years and above increased significantly over time. - In contrast, childhood leprosy cases declined significantly during the study period.

The findings highlight the continued importance of early case detection, community awareness, timely treatment, contact tracing, and strengthened surveillance in efforts to control and eliminate leprosy in Tanzania.

Summary as published by the college when announcing this work. See the journal article for the full abstract.